As you follow the main quest arc for a single faction, the quests for the other factions (with the exception of Independent/Yes Man quests) will fail as you gain infamy for siding against them when you progress through the quests for whichever faction you side with.
Main quest arcsįor these quests you must choose one faction to be loyal to.
Note: you can skip the entire story-line of They Went That-a-Way and head straight to The Tops in New Vegas to complete the quest.
